THE APPENDIX

by TAKE

Research, perspective & practical guidance for life on a GLP-1.

More From The Appendix

A black gym bag with a towel, a water bottle and training shoes on a sunlit wooden floor

Nutrition

What Happens to Your Bones When You Lose Weight on a GLP-1?

You're watching the scale, your protein and probably your muscle. Your bones are quietly involved too. Here's what researchers are...

5 min read

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A candlelit restaurant table with a nearly full glass of white wine beside a bottle, olives and shared plates

Everyday Life

Why Does Alcohol Feel Different on a GLP-1?

Alcohol suddenly less appealing on a GLP-1? Human trials are finding changes in craving, drinking and even the early way...

5 min read

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A woman looking in a bathroom mirror, gently touching her jawline and neck

The Research

What Is “Ozempic Face”? Why Your Face and Skin Can Look Different After GLP-1 Weight Loss

“Ozempic face” is the internet's name for facial changes noticed after GLP-1 weight loss. Here's what research shows about volume...

5 min read

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A woman at a kitchen counter looking unenthusiastically at a forkful of chicken from her plate

Nutrition

Why Am I Suddenly Grossed Out by Foods I Used to Love on a GLP-1?

Foods you used to love suddenly sound awful? Research suggests GLP-1 treatment can change appetite, cravings and food preferences. Here's...

5 min read

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A wooden hairbrush full of shed hair resting on a marble bathroom counter

The Research

Why Is My Hair Shedding More After Losing Weight on a GLP-1?

Hair shedding can happen during GLP-1 treatment, but significant weight loss itself may be part of the story. Here's what...

5 min read

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A desk calendar with one day circled and labelled Shot Day, beside a mug of coffee and a pen

GLP-1 101

Why Does My GLP-1 Feel Stronger Some Weeks Than Others?

Your GLP-1 can feel different from one week to the next. Here's what weekly drug levels can explain — and...

5 min read

Read Story
An unmade bed in a dim bedroom at night, lit by a bedside lamp next to a mug and a book

Everyday Life

Exhausted All Day, Wide Awake at Night? Sleep on a GLP-1 Can Get Weird

Fatigue is documented during GLP-1 treatment. Brain fog and disrupted sleep are more complicated. Here's what may be going on...

5 min read

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A woman at a restaurant table covering her mouth with her hand after a meal

GLP-1 101

The Burping, Reflux and Heartburn Nobody Warned You About

Burping, reflux and the infamous sulphur burps can show up during GLP-1 treatment. Here's what may be happening — and...

5 min read

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Feeling nauseous on a GLP-1 even on an empty stomach

GLP-1 101

Why Am I Nauseous on a GLP-1 Even When I Haven't Eaten?

GLP-1 nausea can show up even when you haven't eaten. Here's why an empty stomach may sometimes make it worse...

5 min read

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Why GLP-1 side effects can feel worse after a dose increase

GLP-1 101

Why Do GLP-1 Side Effects Feel Worse After a Dose Increase?

If your stomach suddenly has opinions about your new dose, there may be a reason. GI side effects are more...

5 min read

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A woman in a chunky knit sweater wrapped in a blanket on a couch, holding a warm mug, with snow visible through the window behind her.

Everyday Life

Why Am I So Cold After Losing Weight on a GLP-1?

Feeling colder since losing weight on a GLP-1? There may be a physiological explanation. But it isn't necessarily the medication...

5 min read

Read Story
Can GLP-1s Lead to Nutritional Deficiencies? Here's What the Research Shows

The Research

Can GLP-1s Lead to Nutritional Deficiencies? Here's What the Research Shows

Eating substantially less can make getting enough nutrition more complicated. Emerging research is examining nutritional deficiencies among people using GLP-1...

6 min read

Read Story
The GLP-1 Grocery List Is Probably Shorter Than You Think

Everyday Life

The GLP-1 Grocery List Is Probably Shorter Than You Think

A smaller appetite can leave a surprisingly full refrigerator. Here's how to rethink grocery shopping without turning it into another...

3 min read

Read Story
Do GLP-1s Cause Muscle Loss? Here's What the Research Actually Shows

The Research

Do GLP-1s Cause Muscle Loss? Here's What the Research Actually Shows

Some lean mass can be lost during GLP-1 weight loss, but lean mass isn't the same as muscle. Here's what...

4 min read

Read Story
Why Does Eating Out Feel So Different on a GLP-1?

Everyday Life

Why Does Eating Out Feel So Different on a GLP-1?

Eating out can feel surprisingly different when your appetite changes. Here's how to navigate restaurant portions, fullness and the unexpected...

3 min read

Read Story
Water Is Important. But Is It Always Enough?

Nutrition

Water Is Important. But Is It Always Enough?

Eating and drinking less can change your hydration routine. Here's when plain water may be enough — and when electrolytes...

5 min read

Read Story
Your Appetite Got Smaller. Your Protein Needs Didn't.

Nutrition

Your Appetite Got Smaller. Your Protein Needs Didn't.

When your appetite gets smaller, getting enough protein can become surprisingly difficult. Here's why experts recommend paying attention to protein...

4 min read

Read Story
GLP-1s May Change What You Want to Eat

The Research

GLP-1s May Change What You Want to Eat

New research suggests GLP-1s may influence more than how much we eat, including cravings and the way we respond to...

4 min read

Read Story
Constipation or Diarrhea? Why GLP-1s Can Change Your Digestion

GLP-1 101

Constipation or Diarrhea? Why GLP-1s Can Change Your Digestion

GLP-1s can be associated with both constipation and diarrhea. Here's why digestion can change and where hydration and fibre may...

4 min read

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THE APPENDIX

TAKE the Appendix with you.

Research, perspective and useful things worth knowing about life on a GLP-1.