Across GLP-1 trials the share of weight lost as lean mass depends on the medication: about 26 percent on tirzepatide, and up to 45 percent on semaglutide, with a class-wide average near 30 percent and reported figures ranging from 20 to 50 percent.* Protein intake becomes harder to maintain when appetite drops, and creatine has been studied more than most nutritional ingredients. The Strength System is TAKE Build, TAKE Nourish, and TAKE Hydrate, assembled around the protein and creatine side of holding onto lean mass.*
Why These Three, Together
Strength can leave quietly during rapid weight loss. In the SURMOUNT-1 DXA substudy the placebo group lost the same ratio as tirzepatide, 25 percent against 26 percent, so this is weight loss behaving as weight loss rather than the medication doing something unusual. It is also worth knowing that fat-free mass measured by DXA includes water, glycogen and connective tissue, so it is not skeletal muscle alone. This system covers the protein side and the creatine side at once, and asks you to bring the third part yourself.*
The Daily Routine
One Build serving daily, timing unimportant, consistency everything. One Nourish shake wherever protein falls shortest, for most people the middle of the day. Hydrate in water through the day. Nourish runs 24 servings to the tub, so expect it to finish slightly ahead of the others.
Common Questions
Consult your healthcare provider before starting if you are pregnant, nursing, taking medication, or have a medical condition. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Every claim on this page is sourced, and the places where the evidence stops are written down too. Read what we do not claim, or the full research behind TAKE.
